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Coumarins from Ferulago capillaris and F. brachyloba

2000; Elsevier BV; Volume: 53; Issue: 8 Linguagem: Inglês

10.1016/s0031-9422(99)00524-5

1873-3700

Benedicto Jiménez, Marı́a Concepción Grande, Josefa Anaya, Pascual Torres, M. Grandé,

Advanced Synthetic Organic Chemistry

Four new coumarins, (+)-senecioylprangol, (−)-3′-senecioyloxymarmesin, (+)-3′-hydroxyprantschimgin and (+)-2″-senecioyloxymarmesin, besides 12 known coumarins have been isolated from two Ferulago species. Their structures have been established by spectroscopic methods and partial synthesis. New synthetic 3′-oxocoumarins are also described. There is a remarkable difference in the contents of the most abundant coumarins found in the roots of both species: osthol and aurapten are specific to F. capillaris and F. brachyloba, respectively.