Artigo Revisado por pares

Cyclative cleavage via solid-phase supported stabilized sulfur ylides: synthesis of macrocyclic lactones

2002; Elsevier BV; Volume: 43; Issue: 5 Linguagem: Inglês

10.1016/s0040-4039(01)02258-4

ISSN

1873-3581

Autores

Elena La Porta, Umberto Piarulli, Francesca Cardullo, Alfredo Paio, Stefano Provera, Pierfausto Seneci, Cesare Gennari,

Tópico(s)

Advanced Synthetic Organic Chemistry

Resumo

A new synthesis of macrolactones bearing a cyclopropyl ring condensed to the macrocycle is reported via a cyclization-release strategy making use of solid-phase supported stabilized sulfur ylides.

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