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The Role of Serology in the Diagnosis of Campylobacter pylori Infection

1989; Taylor & Francis; Volume: 24; Issue: sup160 Linguagem: Inglês

10.3109/00365528909091732

1502-7708

J I Wyatt, B J Rathbone,

Viral gastroenteritis research and epidemiology

Circulating antibodies to Campylobacter pylori in patients with campylobacter-associated gastritis are sufficiently specific to allow serodiagnosis of this condition. This is possible by various techniques, the most convenient being enzyme-linked immunosorbent assay. Applications of serodiagnosis are in two areas--in clinical practice, where proper evaluation is still required, and in epidemiology. Here serodiagnosis shows the prevalence of C. pylori in the general population and in specific population groups. A study of C. pylori and dyspeptic symptoms in a group of healthy blood donors showed a significant association between C. pylori and history of peptic ulceration. However in most donors the gastritis was clinically silent.