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Biosynthesis of Zeaxanthin via Mevalonate in Paracoccus Species Strain PTA-3335. A Product-Based Retrobiosynthetic Study †

2002; American Chemical Society; Volume: 67; Issue: 3 Linguagem: Inglês

10.1021/jo016084r

1520-6904

Wolfgang Eisenreich, Adelbert Bacher, A. Berry, Werner Bretzel, Markus Hümbelin, Rual Lopez‐Ulibarri, Anne F. Mayer, Alexei Yeliseev,

Photosynthetic Processes and Mechanisms

Cultures of the zeaxanthin-producing bacterium Paracoccus species strain PTA-3335 (formerly Flavobacterium) were grown with supplements of (13)C-labeled glucose. Zeaxanthin was isolated and analyzed by (13)C NMR spectroscopy. The data showed that the isoprenoid precursors of zeaxanthin were biosynthesized via the mevalonate pathway. The microorganism was found to utilize glucose mainly via the Entner-Doudoroff pathway.