Prolonged Postprandial Increment in Triglycerides and Decreased Postprandial Response of Very Low Density Lipoproteins in Type 2 Diabetics following an Oral Lipid Load
1993; Wiley; Volume: 683; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1993.tb35722.x
ISSN1749-6632
AutoresPatricia A. Weber, Jürgen Schrezenmeir, S. Fenselau, S. Ausieker, Ruth Probst, H. D. ZUCHHOLD, W. Prellwitz, J. Beyer,
Tópico(s)Health Promotion and Cardiovascular Prevention
ResumoAnnals of the New York Academy of SciencesVolume 683, Issue 1 p. 315-321 Prolonged Postprandial Increment in Triglycerides and Decreased Postprandial Response of Very Low Density Lipoproteins in Type 2 Diabetics following an Oral Lipid Load P. WEBER, Corresponding Author P. WEBER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanyAddress for correspondence: Dr. med. Dr. troph. Peter Weber, III. Medizinische Klinik und Poliklinik, Abteilung für Endokrinologie, Universitätsklinik Mainz, Langenbeckstr. 1, 6500 Mainz, Germany.Search for more papers by this authorJ. SCHREZENMEIR, J. SCHREZENMEIR IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorS. FENSELAU, S. FENSELAU IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorS. AUSIEKER, S. AUSIEKER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorR. PROBST, R. PROBST IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorH. D. ZUCHHOLD, H. D. ZUCHHOLD Laboratory for Clinical Chemistry University Clinic Mainz, GermanySearch for more papers by this authorW. PRELLWITZ, W. PRELLWITZ Laboratory for Clinical Chemistry University Clinic Mainz, GermanySearch for more papers by this authorJ. BEYER, J. BEYER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this author P. WEBER, Corresponding Author P. WEBER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanyAddress for correspondence: Dr. med. Dr. troph. Peter Weber, III. Medizinische Klinik und Poliklinik, Abteilung für Endokrinologie, Universitätsklinik Mainz, Langenbeckstr. 1, 6500 Mainz, Germany.Search for more papers by this authorJ. SCHREZENMEIR, J. SCHREZENMEIR IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorS. FENSELAU, S. FENSELAU IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorS. AUSIEKER, S. AUSIEKER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorR. PROBST, R. PROBST IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this authorH. D. ZUCHHOLD, H. D. ZUCHHOLD Laboratory for Clinical Chemistry University Clinic Mainz, GermanySearch for more papers by this authorW. PRELLWITZ, W. PRELLWITZ Laboratory for Clinical Chemistry University Clinic Mainz, GermanySearch for more papers by this authorJ. BEYER, J. BEYER IIIrd Department of Internal Medicine (Internal Medicine-Endocrinology) University Clinic Mainz, GermanySearch for more papers by this author First published: June 1993 https://doi.org/10.1111/j.1749-6632.1993.tb35722.xCitations: 8AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 FONTBONNE, A., E. ESCHWEGE, F. CAMBIEN, J. L. RICHARD, P. DUCIMETIERE, N. THIBULT, J. M. WARNET, J. R. CLAUDE & G. E. ROSSELIN 1989 Hypertriglyceridaernia as a risk factor of coronary heart disease mortality in subjects with impaired glucose tolerance or diabetes. Diabetologia 32: 300–304. 10.1007/BF00265546 PubMedWeb of Science®Google Scholar 2 SCHLIERF, G., P. OSTER, D. SEIDEL, H. RALTZER, B. SCHELLENBERG, C. C. HEUCK & R. L. WICKLEIN 1977 Tagesprofile von Plasmalipiden und Lipoproteinen bei Patienten mit endogener Hypertriglyceridämie (Typ IV Hyperlipoproteinämie). Klin. Wschr. 55: 161–167. 10.1007/BF01469136 CASPubMedWeb of Science®Google Scholar 3 WEINTRAUB, M. S., S. EISENBERG & J. L. BRESLOW 1987 Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. J. Clin. Invest. 79: 1110–1119. 10.1172/JCI112926 PubMedWeb of Science®Google Scholar 4 COHN, J. S., J. R. MCNAMARA, S. D. COHN, J. M. ORDOVAS & E. J. SCHAEFER 1988 Postprandial plasma lipoprotein changes in human subjects of different ages. J. Lipid Res. 29: 469–479. 10.1016/S0022-2275(20)38520-5 CASPubMedWeb of Science®Google Scholar 5 SCHREZENMEIR, J., P. WEBER, R. PROBST, C. LULEY, H. K. BIESALSKI, W. PRELLWITZ, U. KRAUSE & J. BEYER 1992 Postprandial pattern of triglyceride-rich lipoproteins in normal weighted humans after an oral lipid load: Exaggerated triglycerides and altered insulin response in some subjects. Ann. Nutr. Metab., in press. Google Scholar 6 ZILVERSMIT, D. B. 1979 Atherogenesis: A postprandial phenomenon. Circulation 60: 473–485. 10.1161/01.CIR.60.3.473 CASPubMedWeb of Science®Google Scholar 7 SIMPSON, H. S., C. M. WILLIAMSON, T. OLIVECRONA, S. PRINGLE, J. MACLEAN, A. R. LORIMER, F. BONNEFOUS, Y. BOGAIEVSKY, C. J. PACKARD & J. SHEPHERD 1990 Postprandial lipemia, fenofibrate and coronary artery disease. Atherosclerosis 85: 193–202. 10.1016/0021-9150(90)90111-U CASPubMedWeb of Science®Google Scholar 8 BUCOLO, G. & H. DAVID 1973 Quantitative determination of serum triglycerides by the use of enzymes. Clin. Chem. 19: 476–482. 10.1093/clinchem/19.5.476 CASPubMedWeb of Science®Google Scholar 9 SEIDEL, D., H. WIELAND & C. RUPPERT 1973 Improved techniques for assessment of plasma lipoprotein patterns. I. Precipitation in gel after electrophoresis with polyanionic compounds. Clin. Chem. 19: 737–739. CASPubMedWeb of Science®Google Scholar 10 CLARK, L. C. 1971 A new family of polarographic electrodes for the measurements of glucose, ethanol, amino acids and other oxidase substrates. Proc. Int. Union Physiol. Sci. 9: 10–14. Google Scholar 11 MENARD, L., M. E. DEMPSEY, L. A. BLANKSTEIN, H. ALEYASSINE, M. WACKS & J. S. SOELDNER 1980 Quantitative determination of glycosylated hemoglobin A1 by agar gel elektrophoresis. Clin. Chem. 26: 1598–1602. CASPubMedWeb of Science®Google Scholar 12 NIKKILÄ, E. A. & M. KEKKI 1973 Plasma triglyceride transport kinetics in diabetes mellitus. Metabolism 22: 1–22. 10.1016/0026-0495(73)90024-3 PubMedWeb of Science®Google Scholar 13 WICKLMAYR, M., K. RETT, G. DIETZE & H. MEHNERT 1988 Comparison of metabolic clearance rates of MCT/LCT and LCT emulsions in diabetics. J. Parenter. Enteral. Nutr. 12: 68–71. 10.1177/014860718801200168 PubMedWeb of Science®Google Scholar 14 ARORA, R. C., N. AGARWAL, S. ARORA, R. K. GARG & V. MEHRA 1987 Triglyceride tolerance test: Is it feasible?. JAPI 35: 276–278. PubMedGoogle Scholar 15 KATSILAMBROS, N., P. STAVROU, V. MANJARIS, N. MOIRAS, M. MARAGOS, P. SFIKAKIS & G. K. DAIKOS 1978 Serum lipids in diabetics and nondiabetics after a test meal. Diabetologia 15: 244. Web of Science®Google Scholar 16 LEWIS, G. F., N. M. O'MEARA, P. A. SOLTYS, J. D. BLACKMAN, P. H. IVERIUS, W. L. PUGH, G. S. GETZ & K. S. POLONSKY 1991 Fasting hypertriglyceridemia in noninsulindependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities. J. Clin. Endocrinol. Metab. 72: 934–944. 10.1210/jcem-72-4-934 CASPubMedWeb of Science®Google Scholar 17 GINSBERG, H. N. 1987 Very low density lipoprotein metabolism in diabetes mellitus. Diabetes Metab. Rev. 3: 571–589. 10.1002/dmr.5610030209 CASPubMedGoogle Scholar 18 IWAI, M., G. YOSHINO, T. KAZUMI, K. MATSUBA, M. MATSUSHITA, I. IWATANI, M. MORITA & S. BABA 1989 The role of insulin in triglyceride turnover in rats. Diabetes Res. Clin. Pract. 7: S115–S118. 10.1016/0168-8227(89)90097-1 PubMedWeb of Science®Google Scholar 19 TASKINEN, M. R., C. J. PACKARD & J. SHEPHERD 1990 Effect of insulin therapy on metabolic fate of apolipoprotein B-containing lipoproteins in NIDDM. Diabetes 39: 1017–1027. 10.2337/diabetes.39.9.1017 PubMedWeb of Science®Google Scholar 20 ECKEL, R. H. 1989 Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N. Engl. J. Med. 320: 1060–1069. PubMedWeb of Science®Google Scholar 21 NIKKILÁ, E. A., J. K. HUTTUNEN & C. EHNHOLM 1977 Postheparin plasma lipoprotein lipase and hepatic lipase in diabetes mellitus: Relationship to plasma triglyceride metabolism. Diabetes 26: 11–21. CASPubMedWeb of Science®Google Scholar 22 BEHR, S. R. & F. B. KRAEMER 1988 Insulin deficiency decreases lipoprotein lipase secretion by murine macrophages. Diabetes 37: 1076–1081. 10.2337/diabetes.37.8.1076 PubMedWeb of Science®Google Scholar Citing Literature Volume683, Issue1Dietary Lipids and Insulin Action: Proceedings of the Second International Smolenice Insulin SymposiumJune 1993Pages 315-321 ReferencesRelatedInformation
Referência(s)