Inhibition of phytoene dehydrogenation and activation of carotenogenesis in Phycomyces
1989; Elsevier BV; Volume: 28; Issue: 6 Linguagem: Inglês
10.1016/s0031-9422(00)97812-9
ISSN1873-3700
AutoresEduardo R. Bejarano, Enrique Cerdá‐Olmedo,
Tópico(s)Antioxidant Activity and Oxidative Stress
ResumoCinnamic alcohol, thymol, and diphenylamine inhibited phytoene dehydrogenation in Phycomyces blakesleeanus. At the same time the overall activity of the pathway, measured by the total accumulation of carotenes, increased. The activation of the pathway by diphenylamine is a mere consequence of end-product shortage. This activation was not seen in the mutants lacking end-product regulation. The mutant range of cinnamic alcohol coincided with that of dimethyl phthalate and veratrol, two potent activators of carotenogenesis. Cinnamic alcohol was thus probably a member of the phenol group of activators of carotenogenesis, with separate activating and inhibiting actions.
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