Pericarditis in patients with leukemia
1952; Elsevier BV; Volume: 43; Issue: 3 Linguagem: Inglês
10.1016/0002-8703(52)90084-7
ISSN1097-6744
AutoresHoward R. Bierman, Ern Perkins, Paul Ortega,
Tópico(s)Chemotherapy-induced cardiotoxicity and mitigation
Resumo1. Four leukemic patients who developed pericarditis during the course of their illness are reported. Adhesive pericarditis was found at post-mortem examination in two patients with myelogenous leukemia. In the remaining two patients with lymphogenous leukemia, effusion was the major finding. One of the patients with chronic myelogenous leukemia recovered from an episode of pericarditis and survived for eleven months. 2. The electrocardiographic changes in three patients were characterized by tachycardia, low voltage, elevation of ST complexes, and flat to inverted T waves. 3. Peripheral blood leukocyte counts above 100,000 were present in three of the four patients. In the remaining patient, the peripheral blood leukocyte count was consistently below 2,500 per cubic millimeter. 4. It is suggested that pericarditis with cellular infiltration occurs more frequently than usually suspected in leukemic patients and may often contribute to their death.
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