Artigo Acesso aberto Revisado por pares

Marmaricin, a new sesquiterpenoid coumarin from Ferula marmarica L.

1979; Pharmaceutical Society of Japan; Volume: 27; Issue: 12 Linguagem: Inglês

10.1248/cpb.27.3153

ISSN

1347-5223

Autores

A.M. Dawidar, E. A. Abu‐Mustafa, GUNTER RUCKER, Ezz El-Din A.M. El-Khrisy, RAGAA ABBAS,

Tópico(s)

Genomics, phytochemicals, and oxidative stress

Resumo

A new sesquiterpenoid coumarin, marmaricin, C24H30O4, was isolated from the roots of Ferula marmarica L., grown in Egypt. The carbon skeleton of the sesquiterpenoid moiety was identified by selenium dehydrogenation, yielding 1, 2, 5, 6-tetramethylnaphthalene. The coumarin moiety was determined by acid cleavage to give umbelliferone. The structure of marmaricin was assigned on the basis of spectral and chemical evidence.

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