Portal de Periódicos da CAPES

Primary Melanoma of Skin of the Breast Region

1977; Lippincott Williams & Wilkins; Volume: 185; Issue: 1 Linguagem: Inglês

10.1097/00000658-197701000-00003

1528-1140

Yeu‐Tsu N. Lee, Frank C. Sparks, Donald L. Morton,

Nonmelanoma Skin Cancer Studies

Primary melanoma of skin of the breast region accounted for less than 5% of all malignant melanomas. During a two-year period, 12 patients were seen with these unique lesions. It appears that wide excision and prophylactic lymphadenectomy, including radical mastectomy, gave the best long-term local and regional control. Dissection of the internal mammary nodes did not seem to be beneficial. Pertinent literatures emphasizing several important pathological factors which correlate with highgher incidence of metastases to the regional lymph nodes are reviewed. A rational therapeutic approach, synthesizing above information and incorporating postoperative adjuvant immunotherapy, is suggested.