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A New Multi-Charged C60 Derivative: Synthesis and Biological Properties

2002; Wiley; Volume: 2002; Issue: 17 Linguagem: Inglês

10.1002/1099-0690(200209)2002

1434-193X

Claudia Cusan, Tatiana Da Ros, Giampiero Spalluto, Sarah Foley, Jean‐Marc Janot, P. Seta, Christian Larroque, Maria Cristina Tomasini, Tiziana Antonelli, Luca Ferraro, Maurizio Prato,

Polymer Nanocomposite Synthesis and Irradiation

European Journal of Organic ChemistryVolume 2002, Issue 17 p. 2928-2934 Full Paper A New Multi-Charged C60 Derivative: Synthesis and Biological Properties Claudia Cusan, Claudia Cusan Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorTatiana Da Ros, Tatiana Da Ros daros@units.it Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorGiampiero Spalluto, Giampiero Spalluto Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorSarah Foley, Sarah Foley I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorJean-Marc Janot, Jean-Marc Janot I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorPatrick Seta, Patrick Seta I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorChristian Larroque, Christian Larroque INSERM U128 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorMaria Cristina Tomasini, Maria Cristina Tomasini Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorTiziana Antonelli, Tiziana Antonelli Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorLuca Ferraro, Luca Ferraro Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorMaurizio Prato, Maurizio Prato Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this author Claudia Cusan, Claudia Cusan Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorTatiana Da Ros, Tatiana Da Ros daros@units.it Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorGiampiero Spalluto, Giampiero Spalluto Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this authorSarah Foley, Sarah Foley I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorJean-Marc Janot, Jean-Marc Janot I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorPatrick Seta, Patrick Seta I. E. M. UMR 5635 CNRS, 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorChristian Larroque, Christian Larroque INSERM U128 1919 route de Mende, 34293, Montpellier, Cedex 5, FranceSearch for more papers by this authorMaria Cristina Tomasini, Maria Cristina Tomasini Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorTiziana Antonelli, Tiziana Antonelli Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorLuca Ferraro, Luca Ferraro Dipartimento di Medicina Clinica e Sperimentale − Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, ItalySearch for more papers by this authorMaurizio Prato, Maurizio Prato Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Fax: (internat.) + 39-040/52-572Search for more papers by this author First published: 08 August 2002 https://doi.org/10.1002/1099-0690(200209)2002:17 3.0.CO;2-ICitations: 42Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract A new water-soluble multi-charged monoadduct fullero[60]pyrrolidine derivative with three ethylene glycol chains and three ammonium groups has been synthesized by means of two alternative synthetic pathways. Increasing the concentration of this C60 derivative did not show a significant modification of concentration of superoxide anion radical O2·−, generated by the xanthine/xanthine oxidase system. Moreover, this C60 derivative was ineffective for neuroprotection in quantitative assessment of a neuronal injury considered to occur via radicals. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002) Citing Literature Volume2002, Issue17September 2002Pages 2928-2934 RelatedInformation