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Somatostatin therapy in l‐asparaginase‐induced pancreatitis

1994; Alan R. Liss, Inc.; Volume: 22; Issue: 6 Linguagem: Inglês

10.1002/mpo.2950220614

1096-911X

Yiu‐fai Cheung, Acw Lee, Gcf Chan, Karen K. L. Chan, YL Lau, C. Y. Yeung,

Neonatal Health and Biochemistry

Abstract L‐Asparaginase‐induced pancreatitis is an uncommon but potentially lethal complication. An 8‐year‐old girl with acute lymphoblastic leukaemia developed acute pancreatitis following treatment with asparaginase. Clinical and laboratory improvements were evident after treatment with somatostatin, with no complications of pancreatitis. Induction therapy for the leukaemia was able to be continued and complete remission was documented during the course of pancreatitis and somatostatin treatment, suggesting a beneficial role of somatostatin in the management of asparaginase‐induced pancreatitis. © 1994 Wiley‐Liss, inc.