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Treatment of central giant cell granulmoma of the jaw with calcitonin

1999; Elsevier BV; Volume: 28; Issue: 5 Linguagem: Inglês

10.1034/j.1399-0020.1999.285280513.x

1399-0020

Jan de Lange, Antoine J.W.P. Rosenberg, Hans P. van den Akker, R. Koole, J. J. Wirds, Henk van den Berg,

Sarcoma Diagnosis and Treatment

Giant cell granulmoma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The cmomon therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. In all patients, cmomplete remission of the giant cell granulmoma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.