
Addition of bevacizumab to first-line chemotherapy in advanced colorectal cancer: a systematic review and meta-analysis, with emphasis on chemotherapy subgroups
2012; BioMed Central; Volume: 12; Issue: 1 Linguagem: Inglês
10.1186/1471-2407-12-89
ISSN1471-2407
AutoresLígia Traldi Macedo, André Bacellar Costa Lima, André Deeke Sasse,
Tópico(s)Cancer Treatment and Pharmacology
ResumoBevacizumab has an important role in first-line treatment of metastatic colorectal cancer. However, clinical trials studying its effect have involved distinct chemotherapy regimens with divergent results. The aim of this meta-analysis is to gather current data and evaluate not only the efficacy of bevacizumab, but also the impact of divergent backbone regimens.
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