Dress syndrome secondary to pyrazinamide-A rare case report

2014; Volume: 5; Issue: 6 Linguagem: Inglês

10.7439/ijbar.v5i6.797

ISSN

2455-0558

Autores

Vijaya Patil, Ravindrakumar Pattar, Ravi Ichalkaranji, L S Patil, P Umesh,

Tópico(s)

Mast cells and histamine

Resumo

Drug, rash, hypereosinophilia with systemic symptoms (DRESS syndrome) is life threatening drug induced hypersensitivity reaction. Pyrazinamide has been described as uncommon cause of DRESS syndrome. Here we report a 21 years old female patient had DRESS syndrome on 18 th day of Pyrazinamide exposure. She had generalized pruritic maculopapular rash, fever, lymph node enlargement. Laboratory investigation revealed leucocytosis, eosinophilia, lymphocytosis, raised ESR, thrombocytopenia, raised liver enzymes. Urine examination revealed aseptic pyuria. She recovered completely 6 weeks after drug withdrawal. Here we report this as a rare cas e report of DRESS syndrome due to Pyrazinamide.

Referência(s)