A Comparison of Piribedil, Procyclidine and Placebo in the Control of Phenothiazine-induced Parkinsonism
1977; Cambridge University Press; Volume: 130; Issue: 6 Linguagem: Inglês
10.1192/bjp.130.6.581
ISSN1472-1465
AutoresR. H. S. Mindham, Pauline Lamb, Rachel Bradley,
Tópico(s)Neuroscience and Neuropharmacology Research
ResumoSummary A double-blind, cross-over trial of the effectiveness of piribedil, procyclidine and placebo in the control of parkinsonism induced by fluphenazine decanoate was conducted in sixteen cases of chronic schizophrenia. Procyclidine was shown to be more effective and piribedil less effective than the placebo. Piribedil produced a number of unpleasant effects, including headache, vomiting and malaise.
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