Artigo Acesso aberto Revisado por pares

Regional Differences in Metronidazole Resistance and Increasing Clarithromycin Resistance among Helicobacter pylori Isolates from Japan

2000; American Society for Microbiology; Volume: 44; Issue: 8 Linguagem: Inglês

10.1128/aac.44.8.2214-2216.2000

ISSN

1098-6596

Autores

Mototsugu Kato, Yoshio Yamaoka, Jae J. Kim, Rita Reddy, Masahiro Asaka, Kei Kashima, Michael S. Osato, F A el-Zaatari, David Y. Graham, Dong H. Kwon,

Tópico(s)

Veterinary medicine and infectious diseases

Resumo

ABSTRACT The patterns of antibiotic resistance in Helicobacter pylori were assessed in two different regions in Japan. Overall, prevalences of resistance to metronidazole and clarithromycin were 12.4 and 12.9%, respectively. While there was no difference in clarithromycin resistance, the prevalence of metronidazole resistance was significantly higher in Kyoto (23.8%) than in Sapporo (8.1%). From 1996 to 1999, the prevalence of metronidazole resistance did not change but the prevalence of clarithromycin resistance doubled (from 9.1 to 18.7%).

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