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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Frequencies of ABO, MNSs, and Duffy Phenotypes Among Blood Donors and Malaria Patients from Four Brazilian Amazon Areas

2006; Wayne State University Press; Volume: 78; Issue: 2 Linguagem: Inglês

10.1353/hub.2006.0034

ISSN

1534-6617

Autores

Carlos Eugênio Cavasini, Luíz Carlos de Mattos, Renata Tomé Alves, Álvaro Augusto Ribeiro D'Almeida Couto, Vanja Sueli Pachiano Calvosa, Cláudia R. Bonini-Domingos, Lilian Castilho, Andréa Regina Baptista Rossit, Ricardo Luiz Dantas Machado,

Tópico(s)

Complement system in diseases

Resumo

We compared the serological phenotypic frequencies of ABO, MNSs, and Duffy in 417 blood donors and 309 malaria patients from four Brazilian Amazon areas. Our results suggest no correlation between ABO phenotype and malaria infection in all areas studied. We observed significant correlation between the S+s+, S+s-, and S-s+ phenotypes and malaria infection in three areas. Some of the Duffy phenotypes showed significant correlation between donors and malaria patients in different areas. These data are an additional contribution to the establishment of differential host susceptibility to malaria.

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