Artigo Acesso aberto Produção Nacional Revisado por pares

Acute myocardial infarction: one century of history

2001; Sociedade Brasileira de Cardiologia (SBC); Volume: 77; Issue: 6 Linguagem: Inglês

10.1590/s0066-782x2001001200011

ISSN

1678-4170

Autores

Rogério Sarmento‐Leite, Ana Maria Rocha Krepsky, Carlos Antônio Mascia Gottschall,

Tópico(s)

Cardiac electrophysiology and arrhythmias

Resumo

Acute Myocardial Infarction. One Century of History UpdateCoronary thrombosis has been a known cause of death since the beginning of the 19 th century.On the basis of animal experiments, in which 1 coronary artery was ligated, and limited observations on human postmortem examinations, coronary thrombosis was considered a fatal clinical entity.In 1901, the German Krehl reported that coronary thrombosis not always caused sudden death and that it could be complicated by formation of a ventricular aneurysm and myocardial rupture.These observations were confirmed years later by Obrastov, Strazhesko, and Herrick, who reported the clinical characteristics of acute myocardial infarction and established the differential diagnosis with angina pectoris 1 .As soon as it became evident that one could survive an acute myocardial infarction, attention was drawn to its treatment.In 1912, James Herrick established the importance of rest in postinfarction recovery; rest was the only therapeutic orientation existing at that time, and it was prescribed in an exaggerated way until the beginning of the 1950s.Patients were required to stay bedridden for up to 6 weeks, and were even forbidden to move or to feed themselves during the first week 2 .James Herrick was also responsible for introducing electrocardiography, which was created by Einthoven in 1902, and has been the major diagnostic tool for acute myocardial infarction up until the present time 1 .In 1923, Wearn reported the first consecutive series of 19 patients with the clinicopathologic diagnosis of infarction.These patients were prescribed absolute rest, hydric restriction, and use of digitalis for pulmonary congestion, and caffeine and camphor for preventing and treating hypotension, syncope, and cardiac conduction blocks.Five years later, Parkinson and Bedford reported their experience with the use of morphine to relieve pain in a series of 100 patients with acute myocardial infarction.Nitrates were con-

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