The Value and Complications of Percutaneous Transthoracic Lung Aspiration for the Etiologic Diagnosis of Community-Acquired Pneumonia
1999; Elsevier BV; Volume: 116; Issue: 6 Linguagem: Inglês
10.1378/chest.116.6.1716
ISSN1931-3543
AutoresJ. Anthony G. Scott, Andrew J. Hall,
Tópico(s)Pneumocystis jirovecii pneumonia detection and treatment
ResumoDiagnosis of pneumonia is frustratingly incomplete, with most large studies failing to identify a causative organism in 33 to 45% of patients.123 Diagnosis by blood culture is highly specific, but the sensitivity of blood cultures for bacterial pneumonia is < 25%. An etiology can be obtained in undiagnosed cases by culture of sputum or from serologic diagnoses, but these techniques lack specificity or produce an unconvincing description with multiple pathogens.456 The most convincing evidence of etiology in observational studies of acute pneumonia is the demonstration of a single pathogen in the diseased tissue of the patient and the absence of this same organism from equivalent tissue in healthy control subjects.
Referência(s)