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A Hierarchical Assembly Process to Engineer a Hydrophobic Core for Virus‐like Particles

2010; Wiley; Volume: 49; Issue: 52 Linguagem: Inglês

10.1002/anie.201005548

1521-3773

Zhaohui Su, Qian Wang,

Respiratory viral infections research

Angewandte Chemie International EditionVolume 49, Issue 52 p. 10048-10050 Highlight A Hierarchical Assembly Process to Engineer a Hydrophobic Core for Virus-like Particles† Prof. Zhaohui Su, Prof. Zhaohui Su State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. ChinaSearch for more papers by this authorProf. Qian Wang, Corresponding Author Prof. Qian Wang wang@mail.chem.sc.edu Department of Chemistry & Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208 (USA), Fax: (+1) 803-777-9521Department of Chemistry & Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208 (USA), Fax: (+1) 803-777-9521Search for more papers by this author Prof. Zhaohui Su, Prof. Zhaohui Su State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. ChinaSearch for more papers by this authorProf. Qian Wang, Corresponding Author Prof. Qian Wang wang@mail.chem.sc.edu Department of Chemistry & Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208 (USA), Fax: (+1) 803-777-9521Department of Chemistry & Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208 (USA), Fax: (+1) 803-777-9521Search for more papers by this author First published: 25 November 2010 https://doi.org/10.1002/anie.201005548Citations: 13 † Z.S. thanks the National Natural Science Foundation of China (50921062) for support. Q.W. acknowledges the NSF-CAREER program, DoD-W911NF-09-1-236, DoE-BES, the Alfred P. Sloan Foundation, and the Camille Dreyfus Teacher Scholar Awards Program for financial support. Q.W. is also grateful to CIAC for a guest professorship. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Re-engineer the core: The genomic core of a virus (left) can be re-engineered by the coassembly of viral coat proteins and DNA amphiphiles to produce virus-like nanocarriers to transport both hydrophobic and hydrophilic compounds. It is a general strategy for adapting virus-based vehicles for drug-delivery applications. Citing Literature Volume49, Issue52December 27, 2010Pages 10048-10050 RelatedInformation