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Artigo Revisado por pares
BIBTEX RIS

The effects of prolactin and TSH on thyroid function in Fundulus heteroclitus

1977; Elsevier BV; Volume: 33; Issue: 3 Linguagem: Inglês

10.1016/0016-6480(77)90047-8

ISSN

1095-6840

Autores

E. Gordon Grau, Milton H. Stetson,

Tópico(s)

Reproductive biology and impacts on aquatic species

Resumo

Treatment with ovine prolactin significantly reduces serum T4 in Fundulus heteroclitus, both in control (P < 0.05) and TSH-stimulated fish (P < 0.01), without affecting thyroidal radioiodine uptake. Prolactin also reduces the loss of radioiodine from F. heteroclitus (P < 0.001). This loss is markedly increased by ovine TSH (P < 0.001), but only in the absence of prolactin. Although other explanations are possible, prolactin is probably goiterogenic in F. heteroclitus, lowering thyroidal secretion of T4 as well as inhibiting the peripheral effects of this hormone.

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