Artigo Acesso aberto Produção Nacional Revisado por pares

Evaluation of the efficacy of hydrated sodium aluminosilicate in the prevention of aflatoxin-induced hepatic cancer in rainbow trout

2011; Colégio Brasileiro de Patologia Animal (CBPA); Volume: 31; Issue: 9 Linguagem: Inglês

10.1590/s0100-736x2011000900005

ISSN

1678-5150

Autores

Sarah Arana, M.L. Dagli, Myrna Sabino, Yara Aiko Tabata, Marcos Guilherme Rigolino, Francisco Javier Hernandez‐Blazquez,

Tópico(s)

Meat and Animal Product Quality

Resumo

The use of aluminum silicates for decontaminating animal feed containing aflatoxins has yielded encouraging results in chicken and turkey poults. In contrast, very few studies have tested these substances in aquaculture. In this work, we investigated the efficacy of a trout diet containing 0.5% hydrated sodium aluminosilicate (HSAS) in protecting against contamination with aflatoxin B1. Trout were reared on these diets for one year and the experimental groups were examined monthly for hepatic presumptive preneoplastic and neoplastic lesions. Regardless of the presence of HSAS, all of the fish that received aflatoxin in their diet have shown hepatic lesions indicative of a carcinogenic process, presenting also the development of cancer in some fish. The concentration of HSAS used in this study was ineffective in preventing the onset of hepatic lesions induced by aflatoxin B1 in rainbow trout.

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