70-kVp High-pitch Computed Tomography Pulmonary Angiography with 40 mL Contrast Agent
2015; Elsevier BV; Volume: 22; Issue: 12 Linguagem: Inglês
10.1016/j.acra.2015.08.026
ISSN1878-4046
AutoresLi Xie, Qian Ni, U. Joseph Schoepf, Julian L. Wichmann, Lloyd M. Felmly, Qi Li, Xiang Kong, Chang Sheng Zhou, Song Luo, Long Jiang Zhang, Guangming Lu,
Tópico(s)Radiation Dose and Imaging
ResumoTo assess image quality, radiation dose, and diagnostic accuracy of 70-kVp high-pitch computed tomography pulmonary angiography (CTPA) using 40 mL contrast agent and sinogram affirmed iterative reconstruction (SAFIRE) compared to 100-kVp CTPA using 60 mL contrast agent and filtered back projection.Eighty patients underwent CTPA at either 70 kVp (group A, n = 40; 3.2 pitch, 40 mL contrast medium, and SAFIRE) or 100 kVp (group B, n = 40; 1.2 pitch, 60 mL contrast medium, and filtered back projection). Signal-to-noise ratio and contrast-to-noise ratio were calculated. Subjective image quality was evaluated using a five-grade scale, and diagnostic accuracy was assessed. Radiation doses were compared.Computed tomography values, signal-to-noise ratio, and contrast-to-noise ratio of pulmonary arteries were higher in group A compared to group B (all P < 0.001). Subjective image quality showed no difference between the two groups (P = 0.559) with good interobserver agreement (κ = 0.647). No difference was found regarding diagnostic accuracy between the two groups (P > 0.05). The effective dose for group A was lower by 80% compared to group B (P < 0.001).70-kVp high-pitch CTPA with reduced contrast media and SAFIRE provides comparable image quality and substantial radiation dose savings compared to a routine CTPA protocol.
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