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Protein–RNA Interfaces Probed by 1 H‐Detected MAS Solid‐State NMR Spectroscopy

2013; Wiley; Volume: 52; Issue: 8 Linguagem: Inglês

10.1002/anie.201208024

ISSN

1521-3773

Autores

Sam Asami, Magdalena Rakwalska‐Bange, Teresa Carlomagno, Bernd Reif,

Tópico(s)

Electron Spin Resonance Studies

Resumo

Angewandte Chemie International EditionVolume 52, Issue 8 p. 2345-2349 Communication Protein–RNA Interfaces Probed by 1H-Detected MAS Solid-State NMR Spectroscopy† Sam Asami, Sam Asami Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany) Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstrasse 1, 85764 Neuherberg (Germany)Search for more papers by this authorMagdalena Rakwalska-Bange, Magdalena Rakwalska-Bange Computational and Structural Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg (Germany)Search for more papers by this authorDr. Teresa Carlomagno, Dr. Teresa Carlomagno Computational and Structural Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg (Germany)Search for more papers by this authorProf. Dr. Bernd Reif, Corresponding Author Prof. Dr. Bernd Reif [email protected] Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany) Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstrasse 1, 85764 Neuherberg (Germany)Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany)===Search for more papers by this author Sam Asami, Sam Asami Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany) Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstrasse 1, 85764 Neuherberg (Germany)Search for more papers by this authorMagdalena Rakwalska-Bange, Magdalena Rakwalska-Bange Computational and Structural Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg (Germany)Search for more papers by this authorDr. Teresa Carlomagno, Dr. Teresa Carlomagno Computational and Structural Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg (Germany)Search for more papers by this authorProf. Dr. Bernd Reif, Corresponding Author Prof. Dr. Bernd Reif [email protected] Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany) Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstrasse 1, 85764 Neuherberg (Germany)Munich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM), Lichtenbergstrasse 4, 85747 Garching (Germany)===Search for more papers by this author First published: 18 January 2013 https://doi.org/10.1002/anie.201208024Citations: 49 † We thank the Leibniz-Institut für Molekulare Pharmakologie (FMP) for providing measurement time and U. Fink for technical assistance in the lab. This work was performed in the framework of SFB 1035 of the German Research Foundation. MAS=magic-angle-spinning. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Both protonated and deuterated samples were employed in the study of the L7Ae box C/D RNA complex by 1H-detected solid-state NMR spectroscopy. 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