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The Impact of Cigarette Smoking on Stimulant Addiction

2009; Taylor & Francis; Volume: 35; Issue: 1 Linguagem: Inglês

10.1080/00952990802326280

1097-9891

Andrea H. Weinberger, Mehmet Sofuoglu,

Neurotransmitter Receptor Influence on Behavior

Objectives: Stimulant users smoke cigarettes at high rates; however, little is known about the relationship between tobacco and stimulants. Methods: Our goal in this article is to synthesize a growing literature on the role of cigarette smoking in stimulant addiction. Results: Early nicotine exposure may influence the development of stimulant addiction. Preclinical and clinical studies suggest a facilitatory role of nicotinic agonists for stimulant addiction. Smoking appears to be associated with more severe stimulant use and poorer treatment outcomes. Conclusions: It is important to assess smoking and smoking-related variables within stimulant research studies to more fully understand the comorbidity. Integrating smoking cessation into stimulant treatment may improve nicotine and stimulant treatment outcomes.