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Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit

2013; Oxford University Press; Volume: 58; Issue: 5 Linguagem: Inglês

10.1093/cid/cit807

1537-6591

James Price, Tanya Golubchik, Kevin Cole, D. J. Wilson, Derrick W. Crook, Guy Thwaites, Rory Bowden, Andrew Walker, Tim Peto, John R. Paul, Martin Llewelyn,

Mycobacterium research and diagnosis

Background. Strategies to prevent Staphylococcus aureus infection in hospitals focus on patient-to-patient transmission. We used whole-genome sequencing to investigate the role of colonized patients as the source of new S. aureus acquisitions, and the reliability of identifying patient-to-patient transmission using the conventional approach of spa typing and overlapping patient stay.