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A comparison of artificial saliva and pilocarpine in radiation induced xerostomia

1994; Cambridge University Press; Volume: 108; Issue: 8 Linguagem: Inglês

10.1017/s0022215100127768

1748-5460

Andrew Davies, Jamie J. Singer,

Oral health in cancer treatment

Abstract Twenty patients with radiation-induced xerostomia were entered into a prospective randomized crossover study comparing a mucin-based artificial saliva (Saliva Orthana) and a mouthwash containing pilocarpine 5 mg three times a day. Overall the patients found that the pilocarpine mouthwash was more effective than the artificial saliva in relieving their symptoms ( p = 0.04), and 47 per cent of the patients wanted to continue with this treatment after the study had finished.