Artigo Acesso aberto Revisado por pares

Identification of Genes Encoding the Folate- and Thiamine-Binding Membrane Proteins in Firmicutes

2008; American Society for Microbiology; Volume: 190; Issue: 22 Linguagem: Inglês

10.1128/jb.01070-08

ISSN

1098-5530

Autores

Aymerick Eudes, Guus B. Erkens, Dirk Jan Slotboom, Dmitry A. Rodionov, Valeria Naponelli, Andrew D. Hanson,

Tópico(s)

RNA and protein synthesis mechanisms

Resumo

Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified in the Lactobacillus casei genome, expressed in Lactococcus lactis, and functionally characterized. Similar genes occur in many Firmicutes, sometimes next to folate or thiamine salvage genes. Most thiT genes are preceded by a thiamine riboswitch.

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