Synthesis of Enol Ethers and Enamines by Pd‐Catalyzed Tosylhydrazide‐Promoted Cross‐Coupling Reactions
2009; Wiley; Volume: 15; Issue: 48 Linguagem: Inglês
10.1002/chem.200902718
ISSN1521-3765
AutoresJosé Barluenga, María Escribano, Patrícia Moriel, Fernándo Aznar, Carlos Valdés,
Tópico(s)Catalytic Cross-Coupling Reactions
ResumoChemistry – A European JournalVolume 15, Issue 48 p. 13291-13294 Communication Synthesis of Enol Ethers and Enamines by Pd-Catalyzed Tosylhydrazide-Promoted Cross-Coupling Reactions José Barluenga Prof., José Barluenga Prof. [email protected] Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorMaría Escribano, María Escribano Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorPatricia Moriel Dr., Patricia Moriel Dr. Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorFernando Aznar Prof., Fernando Aznar Prof. Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorCarlos Valdés Dr., Carlos Valdés Dr. [email protected] Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this author José Barluenga Prof., José Barluenga Prof. [email protected] Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorMaría Escribano, María Escribano Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorPatricia Moriel Dr., Patricia Moriel Dr. Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorFernando Aznar Prof., Fernando Aznar Prof. Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this authorCarlos Valdés Dr., Carlos Valdés Dr. [email protected] Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, c/Julián Clavería 8. Oviedo 33006 (Spain), Fax: (+34) 985103450Search for more papers by this author First published: 08 December 2009 https://doi.org/10.1002/chem.200902718Citations: 84Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract α-Substitution is fine: α-Alkoxycarbonyl and α-aminocarbonyl compounds are good substrates for the recently developed tosylhydrazide-promoted Pd-catalyzed cross-coupling of carbonyls with aryl halides. The reaction gives rise to enol ethers and enamines, respectively, which are useful synthetic intermediates in heterocyclic synthesis. Otherwise, they can be hydrolyzed to give α,α-disubstituted aldehydes. Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description chem_200902718_sm_miscellaneous_information.pdf6.8 MB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. 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