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Single Extra‐Amniotic Injection of Prostaglandin E 2 in Tylose Gel to Induce First Trimester Abortion in Young Nullipara

1982; Informa; Volume: 61; Issue: 5 Linguagem: Inglês

10.3109/00016348209156588

1600-0412

O. Djahanbakhch, T. S. Bassan, Durwood. Marshall, Noah Gardner,

Ectopic Pregnancy Diagnosis and Management

Abstract. A single extra‐amniotic injection of 2 or 4 mg of prostaglandin E 2 in Tylose gel was administerd to 30 primi‐gravidae between the ages of 14 and 20 years to induce first‐trimester abortion. Twenty‐three patients (76.7%) aborted, though incompletely, within 9 hours, with a mean induction‐abortion interval of 6.3 hours. In the remaining 7 (23.3%) the cervical os was found to be open and no mechanical dilatation was required at the time of vacuum aspiration. The only side effect was vomiting, which occurred in 2 patients. The method was shown to be safe and effective and may be employed in young primigravidae, thus eliminating the cervical complications attending vacuum aspiration.