Disseminated Histoplasmosis in the Acquired Immune Deficiency Syndrome
1984; American Medical Association; Volume: 144; Issue: 11 Linguagem: Inglês
10.1001/archinte.1984.04400020049006
ISSN1538-3679
Autores Tópico(s)Pneumocystis jirovecii pneumonia detection and treatment
Resumo[ill]atients with acquired immune deficiency syndrome (AIDS) are susceptible to infection with a [ill]riety of opportunistic pathogens. Pneumocystis [ill]inii pneumonia is the major opportunistic infec[ill]n associated with the syndrome, while Candida [ill]icans and Cryptococcus neoformans are the most [ill]mmon fungi causing disease in AIDS. 1 We first [ill]spected that AIDS predisposed to disseminated [ill]toplasmosis in a patient we examined in 1981. 2 [ill]ce then, the association has been clearly established, with 15 cases reported in six US cities 3-7 and in Trinidad. 8 Only one of these occurred outside an endemic area. 6 Of 19 patients with AIDS examined by either Bonner and co-workers 3 in Birmingham, Ala, in this issue (four patients) or by Zeckel et al (unpublished observations) in Indianapolis (15 patients), ten patients (53%) had disseminated histoplasmosis, clearly demonstrating the prevalence of this opportunistic infection in patients with AIDS residing in endemic areas. Early localization of AIDS to New York City and San Francisco
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