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Novel Avian Influenza H7N3 Strain Outbreak, British Columbia

2004; Centers for Disease Control and Prevention; Volume: 10; Issue: 12 Linguagem: Inglês

10.3201/eid1012.040743

1080-6059

Martin Hirst, Caroline R. Astell, Malachi Griffith, Shaun Coughlin, Michelle Moksa, Thomas Zeng, Duane E. Smailus, Robert A. Holt, Steven J.M. Jones, Marco A. Marra, Martin Petric, Mel Krajden, David S. Lawrence, Annie Mak, Ron Chow, Danuta M. Skowronski, Sam Tweed, Swee-Han Goh, Robert C. Brunham, John A. Robinson, Victoria Bowes, Ken Sojonky, Seán Byrne, Yan Li, Darwyn Kobasa, Tim Booth, Mark Paetzel,

Viral gastroenteritis research and epidemiology

Genome sequences of chicken (low pathogenic avian influenza [LPAI] and highly pathogenic avian influenza [HPAI]) and human isolates from a 2004 outbreak of H7N3 avian influenza in Canada showed a novel insertion in the HA0 cleavage site of the human and HPAI isolate. This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus.