Rapid Determination of Paracetamol in Blood Serum Samples by First-Derivative UV Absorption Spectroscopy
1995; Taylor & Francis; Volume: 28; Issue: 12 Linguagem: Inglês
10.1080/00032719508000040
ISSN1532-236X
AutoresPatricia C. Damiani, Marı́a É. Ribone, Alejandro C. Olivieri,
Tópico(s)Analytical Methods in Pharmaceuticals
ResumoAbstract A rapid method for the determination of paracetamol in human blood serum using first-derivative UV absorption spectroscopy is described. It involves no sample pretreatment, extraction or derivatization procedures, other than a standard deproteinizing technique with trichloroacetic acid. The results can be applied to both therapeutic and toxic levels of paracetamol.
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