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BIBTEX RIS

Dishevelled and Wnt signaling: is the nucleus the final frontier?

2005; BioMed Central; Volume: 4; Issue: 1 Linguagem: Inglês

10.1186/jbiol22

ISSN

1478-5854

Autores

Raymond Habas, Igor B. Dawid,

Tópico(s)

Kruppel-like factors research

Resumo

The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca2+ pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of nuclear localization of Dsh for pathway-specific activation.

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