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BIBTEX RIS

Investigation of the antimycobacterial activity of 36 plant extracts from the brazilian Atlantic Forest

2008; UNIVERSIDADE DE SÃO PAULO; Volume: 44; Issue: 4 Linguagem: Inglês

10.1590/s1516-93322008000400013

ISSN

1809-4562

Autores

Daniela Fernandes Ramos, Gilda Guimarães Leitão, Fernanda das Neves Costa, Lisandra Ferreira de Abreu, Javier Vargas Villarreal, Suzana Guimarães Leitão, Salvador Luis Said y Fernández, Pedro Eduardo Almeida da Silva,

Tópico(s)

Bioactive Compounds and Antitumor Agents

Resumo

Thirty-six plant extracts from the brazilian Atlantic Forest were tested for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv and M. kansasii, using the method REMA in seriate concentrations of 100 to 0.20 µg/mL. Among the thirty six extracts tested, five were active against M. tuberculosis, and three of these extracts also showed activity against M. kansasii. Cytotoxicity test with VERO cells was performed with the five extracts active against M. tuberculosis. Only the extract of Peschiera affinis was identified as non-toxic in the concentration of 100µg/mL.

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