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New developments in the InterPro database

2007; Oxford University Press; Volume: 35; Issue: Database Linguagem: Inglês

10.1093/nar/gkl841

1362-4962

Nicola Mulder, Rolf Apweiler, Teresa K. Attwood, Amos Bairoch, Alex Bateman, David Binns, Peer Bork, V. Buillard, Lorenzo Cerutti, Richard R. Copley, Emmanuel Courcelle, Ujjwal Das, Louise C. Daugherty, Mark Dibley, ROBERT FINN, Wolfgang Fleischmann, Julian Gough, Daniel H. Haft, Nicolas Hulo, Sarah Hunter, Daniel Kahn, Alexander Kanapin, Anish Kejariwal, Alberto Labarga, Petra Langendijk-Genevaux, D. Lonsdale, Rodrigo López, Ivica Letunić, Martin Madera, John Maslen, Craig McAnulla, J. McDowall, Jaina Mistry, Alex Mitchell, A. N. NIKOL'SKAYA, Sandra Orchard, C. Orengo, Robert Petryszak, J. D. Selengut, Christian Sigrist, Paul D. Thomas, F. Valentin, Derek A. Wilson, Cathy Wu, Corin Yeats,

Enzyme Structure and Function

InterPro is an integrated resource for protein families, domains and functional sites, which integrates the following protein signature databases: PROSITE, PRINTS, ProDom, Pfam, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D and PANTHER. The latter two new member databases have been integrated since the last publication in this journal. There have been several new developments in InterPro, including an additional reading field, new database links, extensions to the web interface and additional match XML files. InterPro has always provided matches to UniProtKB proteins on the website and in the match XML file on the FTP site. Additional matches to proteins in UniParc (UniProt archive) are now available for download in the new match XML files only. The latest InterPro release (13.0) contains more than 13 000 entries, covering over 78% of all proteins in UniProtKB. The database is available for text- and sequence-based searches via a webserver (Author Webpage), and for download by anonymous FTP (Author Webpage). The InterProScan search tool is now also available via a web service at Author Webpage.