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Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial

2012; American Association for the Advancement of Science; Volume: 4; Issue: 152 Linguagem: Inglês

10.1126/scitranslmed.3004214

1946-6242

Elizabeth Berry‐Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton–Bowen, Yi Mu, Danh V. Nguyen, Joseph Gonzalez‐Heydrich, Paul P. Wang, Randall L. Carpenter, Mark F. Bear, Randi J. Hagerman,

Family and Disability Support Research

Administration of a selective GABA B agonist to individuals with fragile X syndrome improves their deficits in social avoidance, a core symptom of the disease.