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BIBTEX RIS

VENTILATORY RESPONSE TO CARBON DIOXIDE IN PATIENTS WITH HOMOZYGOUS SICKLE-CELL DISEASE

1976; Elsevier BV; Volume: 48; Issue: 3 Linguagem: Inglês

10.1093/bja/48.3.249

ISSN

1471-6771

Autores

O O Elegbeleye, A O Afonja, D Femi-Pearse, F. I. Akinsete,

Tópico(s)

Hematological disorders and diagnostics

Resumo

The ventilatory response to carbon dioxide was measured by a rebreathing technique in 21 Nigerians who had homozygous sickle-cell disease. The slope of the carbon dioxide response curve was obtained by plotting the ventilation at successive half-minute intervals against the corresponding mean end-tidal PCO2. Our results showed that sickle-cell patients are as sensitive to carbon dioxide as are normal subjects.

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