Familial Acantholysis of Angus Calves
1973; SAGE Publishing; Volume: 10; Issue: 6 Linguagem: Inglês
10.1177/030098587301000601
ISSN1544-2217
AutoresR.D. Jolly, M.R. Alley, P.J. O'Hara,
Tópico(s)RNA regulation and disease
ResumoA disease in Angus calves was characterised by shedding of the epidermis with ulceration and inflammation of the oral mucosa and the skin of carpus, metacarpal-phalangeal joints, phalanges, coronary border, and with partial separation of the hooves. The pathogenesis of these lesions involves a breakdown of intercellular adhesions associated with anomalous development of the desmosome-tonofilament complexes in the basal and prickle cells of the epidermis. The breeding and clinical history suggested a genetic cause. The disease was called ‘familial acantholysis of Angus calves’.
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