PROCALCITONIN AND C-REACTIVE PROTEIN SERUM LEVELS AS MARKERS OF INFECTION IN A PEDIATRIC POPULATION WITH FEBRILE NEUTROPENIA AND CANCER
2009; Taylor & Francis; Volume: 26; Issue: 6 Linguagem: Inglês
10.3109/08880010903044797
ISSN1521-0669
AutoresManuel Martinez-Albarran, Jose de Jesus Perez-Molina, Sergio Gallegos‐Castorena, Fernando Sánchez‐Zubieta, Susana del Toro‐Arreola, Rogelio Troyo‐Sanromán, Óscar González-Ramella,
Tópico(s)Bacterial Identification and Susceptibility Testing
ResumoProcalcitonin and C-reactive-protein are inflammatory markers for sepsis. The authors evaluated their sensitivity and specificity in pediatric patients with cancer and febrile neutropenia.Serum procalcitonin and C-reactive-protein were evaluated. Patients (n = 54) were divided into 2 groups, with severe infection (n = 18) or without documented infection (n = 36).Procalcitonin and C-reactive protein were significantly higher in the high-risk group. Procalcitonin displayed 72.2% sensitivity and 80.5% specificity. C-reactive-protein had a sensitivity of 77.7% and specificity of 77.2%.Procalcitonin is an accurate predictor of bacterial infection in neutropenic children, while C-reactive-protein may be a better screening test in emergency settings.
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