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Survival variations by country and age for lymphoid and myeloid malignancies in Europe 2000–2007: Results of EUROCARE-5 population-based study

2015; Elsevier BV; Volume: 51; Issue: 15 Linguagem: Inglês

10.1016/j.ejca.2015.08.003

1879-0852

Roberta De Angelis, Pamela Minicozzi, Milena Sant, Luigino Dal Maso, David Brewster, Gemma Osca‐Gelis, Otto Visser, Marc Maynadié, Rafael Marcos‐Gragera, Xavier Troussard, Dominic Agius, P. Roazzi, E. Meneghini, Alain Monnereau, Monika Hackl, N. Zielonke, Willi Oberaigner, Erik V. Van der Eycken, K. Henau, Z. Valerianova, Nadya Dimitrova, Mario Šekerija, Miroslav Zvolský, Ladislav Dušek, Hans H. Storm, Gerda Engholm, Margit Mägi, Tiiu Aareleid, Nea Malila, Karri Seppä, Michel Velten, X. Troussard, Véronique Bouvier, Guy Launoy, Anne‐Valérie Guizard, J Faivre, Anne‐Marie Bouvier, P. Arveux, Marc Maynadié, Anne‐Sophie Woronoff, Michel Robaszkiewicz, Isabelle Baldi, Alain Monnereau, Brigitte Trétarre, Nadine Bossard, Aurélien Belot, M. Colonna, F. Molinié, S. Bara, C. Schvartz, B. Lapôtre‐Ledoux, Pascale Grosclaude, M. Meyer, Roland Stabenow, Sabine Luttmann, Andrea Eberle, Hermann Brenner, Alice Nennecke, Jutta Engel, G. Schubert-Fritschle, Joachim Kieschke, Jan Heidrich, Bernd Holleczek, Alexander Katalinic, Jón G. Jónasson, Laufey Tryggvadóttír, Harry Comber, Guido Mazzoleni, A. Bulatko, C. Buzzoni, Adriano Giacomin, A. Sutera Sardo, Pamela Mancuso, Stefano Ferretti, Emanuele Crocetti, Adele Caldarella, Gemma Gatta, Milena Sant, H. Amash, C. Amati, Paolo Baili, Franco Berrino, S. Bonfarnuzzo, Laura Botta, Francesca Di Salvo, Roberto Foschi, C. Margutti, E. Meneghini, Pamela Minicozzi, Annalisa Trama, Diego Serraino, Luigino Dal Maso, R. De Angelis, M. Caldora, Riccardo Capocaccia, E. Carrani, Silvia Francisci, Sandra Mallone, Daniela Pierannunzio, P. Roazzi, Silvia Rossi, Mariano Santaquilani, Andrea Tavilla, Fabio Pannozzo, S. Busco, L Bonelli, Marina Vercelli, Valerio Gennaro, P. Ricci, M. Autelitano, Giorgia Randi, Maurizio Ponz de Leòn, C. Marchesi, Claudia Cirilli, Mario Fusco, M.F. Vitale, M. Usala, A. Traina, R. Staiti, Francesco Vitale, Barbara Ravazzolo, Maria Michiara, ­Rosario ­Tumino, Paolo Giorgi Rossi, E. Di Felice, Fabio Falcini, Antonio Iannelli, O. Sechi, R. Cesaraccio, Silvano Piffer, A Madeddu, F. Tisano, S. Maspero, Anna Clara Fanetti, Roberto Zanetti, Stefano Rosso, P. Candela, T. Scuderi, Fabrizio Stracci, Fortunato Bianconi, Giovanna Tagliabue, Paolo Contiero, Angelo Paolo Dei Tos, Stefano Guzzinati, Santa Pildava, Giedrė Smailytė, Neville Calleja, D. Agius, T.B. Johannesen, Jadwiga Rachtan, Stanisław Góźdż, Ryszard Mężyk, Jan Błaszczyk, Marek Bębenek, Magdalena Bielska‐Lasota, G. Forjaz de Lacerda, María José Bento, Clara Castro, A. Miranda, A. Mayer-da-Silva, Florian Nicula, Daniela Coza, C. Safaei Diba, Maja Primic‐Žakelj, E. Almar, C. Ramírez, M. Errezola, J. Bidaurrazaga, A. Torrella-Ramos, J.M. Díaz García, R. Jimenez-Chillaron, Rafael Marcos‐Gragera, À. Izquierdo, María‐José Sánchez, D.Y.L. Chang, Carmen Navarro, M.D. Chirlaque, Conchi Moreno‐Iribas, Eva Ardanáz, Jaume Galcerán, Marià Carulla, Mats Lambe, S. Khan, Seyed Mohsen Mousavi, C. Bouchardy, M. Usel, S.M. Ess, Henry Clay Frick, Matthias Lorez, S.M. Ess, C. Herrmann, Andrea Bordoni, Alessandra Spitale, Isabelle Konzelmann, Otto Visser, V. Lemmens, Michel P. Coleman, Claudia Allemani, Bernard Rachet, Julia Verne, N. Easey, Gill Lawrence, Teresa Morán, Jem Rashbass, M. Roche, J. Wilkinson, Anna Gavin, David Donnelly, David Brewster, D.W. Huws, Peter D. White, R. Otter,

Acute Myeloid Leukemia Research

Significant advances in the management of patients with lymphoid and myeloid malignancies entered clinical practice in the early 2000's. The EUROCARE-5 study database provides an opportunity to assess the impact of these changes at the population level by country in Europe. We provide survival estimates for clinically relevant haematological malignancies (HM), using the International Classification of Diseases for Oncology 3, by country, gender and age in Europe.We estimated age-standardised relative survival using the complete cohort approach for 625,000 adult patients diagnosed in 2000-2007 and followed up to 2008. Survival information was provided by 89 participating cancer registries from 29 European countries. Mean survival in Europe was calculated as the population weighted average of country-specific estimates.On average in Europe, 5-year relative survival was highest for Hodgkin lymphoma (81%; 40,625 cases), poorest for acute myeloid leukaemia (17%; 57,026 cases), and intermediate for non-Hodgkin lymphoma (59%; 329,204 cases), chronic myeloid leukaemia (53%; 17,713 cases) and plasma cell neoplasms (39%; 94,024 cases). Survival was generally lower in Eastern Europe and highest in Central and Northern Europe. Wider between country differences (>10%) were observed for malignancies that benefited from therapeutic advances, such as chronic myeloid leukaemia, chronic lymphocytic leukaemia, follicular lymphoma, diffuse large B-cell lymphoma and multiple myeloma. Lower differences (<10%) were observed for Hodgkin lymphoma.Delayed or reduced access to innovative and appropriate therapies could plausibly have contributed to the observed geographical disparities between European regions and countries. Population based survival by morphological sub-type is important for measuring outcomes of HM management. To better inform quality of care research, the collection of detailed clinical information at the population level should be prioritised.