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Towards a molecular understanding of dendritic cell immunobiology

2000; Elsevier BV; Volume: 21; Issue: 11 Linguagem: Inglês

10.1016/s0167-5699(00)01736-9

1355-8242

Franca C. Hartgers, Carl G. Figdor, Gosse J. Adema,

vaccines and immunoinformatics approaches

Abstract Dendritic cells (DCs) are professional antigen presenting cells that play a pivotal role in the control of immunity. The molecules and organization of cellular processes that render DCs so effective in stimulating immune responses are actively pursued. Here, we discuss newly identified DC-associated molecules and their role in regulating the unique behavior and function of the antigen presenting DCs.