Voltar
Artigo Revisado por pares
BIBTEX RIS

Synthesis and biodistribution of 8-iodo-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]-diazepine: Iozapine

2007; Elsevier BV; Volume: 17; Issue: 14 Linguagem: Inglês

10.1016/j.bmcl.2007.04.069

ISSN

1464-3405

Autores

Alummoottil V. Joshua, Sanjay Sharma, Alicia Strelkov, John R. Scott, Mathew T. Martin‐Iverson, Douglas N. Abrams, Peter H. Silverstone, Alexander McEwan,

Tópico(s)

Cancer Treatment and Pharmacology

Resumo

8-Iodo-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]-diazepine: Iozapine, a potential D4-receptor ligand was synthesized using oxidative iodo-destannylation reaction. The preliminary biodistribution studies of radioiodinated iozapine have shown that the compound is taken up in the brains of mice and rabbits.

Referência(s)