Recent progress in the field of glycopeptide synthesis
2007; Wiley; Volume: 88; Issue: 2 Linguagem: Inglês
10.1002/bip.20699
ISSN1097-0282
AutoresHironobu Hojo, Yoshiaki Nakahara,
Tópico(s)Chemical Synthesis and Analysis
ResumoAbstract Glycosylation is a common post‐translational modification of proteins. Although its significance in biological system is well recognized, approaches to analyze carbohydrate function are limited. This is because of difficulty in obtaining homogeneous glycoproteins from natural sources. Due to the progress of the carbohydrate and peptide chemistry, syntheses of various homogeneous glycopeptides and glycoproteins, which are suitable for biological studies, have been achieved by chemical means. In this review, we briefly summarize recent advances in the field of glycopeptide synthesis after 1999. © 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 88: 308–324, 2007. This article was originally published online as an accepted preprint. The ‘Published Online’ date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
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