The Role of Nogo and the Mitochondria–Endoplasmic Reticulum Unit in Pulmonary Hypertension
2011; American Association for the Advancement of Science; Volume: 3; Issue: 88 Linguagem: Inglês
10.1126/scitranslmed.3002194
ISSN1946-6242
AutoresGopinath Sutendra, Peter Dromparis, Paulette L. Wright, Sébastien Bonnet, Alois Haromy, Zhengrong Hao, M. Sean McMurtry, Marek Michalak, Jean E. Vance, William C. Sessa, Evangelos D. Michelakis,
Tópico(s)Endoplasmic Reticulum Stress and Disease
ResumoThe endoplasmic reticulum stress protein Nogo is a culprit in the mitochondrial defects that characterize pulmonary hypertension, pointing to therapeutic drug targets.
Referência(s)