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Biogenic Amine Neurotransmitter Transporters: Just When You Thought You Knew Them

2005; American Physiological Society; Volume: 20; Issue: 4 Linguagem: Inglês

10.1152/physiol.00013.2005

1548-9213

Randy Blakely, Louis J. DeFelice, Aurelio Galli,

Biotin and Related Studies

Plasma membrane transporters have long been known to support the reuptake of biogenic amine neurotransmitters following release in the central and peripheral nervous systems. Using high-resolution imaging, patch-clamp and amperometric approaches, as well as molecular manipulations of transporter-regulatory pathways, surprising new details have been uncovered as to how transporters work and are influenced by signaling pathways and psychostimulants.