Artigo Acesso aberto Revisado por pares

Effects of phosphate on vascular function under normal conditions and influence of the uraemic state

2012; Oxford University Press; Volume: 96; Issue: 1 Linguagem: Inglês

10.1093/cvr/cvs240

ISSN

1755-3245

Autores

Isabelle Six, Julien Maizel, Fellype Carvalho Barreto, Ashraf Yusuf Rangrez, Sébastien Dupont, M. Slama, Christophe Tribouilloy, Gabriel Choukroun, J.C. Mazière, Stefanie M. Bode-Boeger, Jan T. Kielstein, Tilman B. Drüeke, Ziad A. Massy,

Tópico(s)

Biomedical Research and Pathophysiology

Resumo

AimsIncreased serum phosphorus levels are associated with cardiovascular disease in patients with chronic kidney disease (CKD) and in the general population. High phosphate levels may play a direct role in vascular dysfunction. We investigated here the effects of phosphate loading and of the phosphate binder sevelamer-HCl on vascular function.

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