Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents
2013; American Medical Association; Volume: 149; Issue: 6 Linguagem: Inglês
10.1001/jamadermatol.2013.2874
ISSN2168-6084
AutoresHarkamal Kaur Randhawa, Jill Hamilton, Elena Pope,
Tópico(s)Chemotherapy-related skin toxicity
ResumoHidradenitis suppurativa (HS) is a chronic debilitating cutaneous disease for which there is no universally effective treatment. Patients typically present at puberty with tender subcutaneous nodules that can progress to dermal abscess formation. Antiandrogens have been used in the treatment of HS, and studies have primarily focused on adult patients.We present a case series of 3 pediatric patients with HS who were successfully treated with oral finasteride, resulting in decreased frequency and severity of disease flares with no significant adverse effects.Finasteride is a therapeutic option that provides benefit for pediatric patients with HS. Further prospective data and randomized controlled studies will provide helpful information in the management of this disease.
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