Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Flavonoids from Dalbergia cearensis

1975; Elsevier BV; Volume: 14; Issue: 5-6 Linguagem: Inglês

10.1016/s0031-9422(00)98663-1

1873-3700

Ismenia Salignac de Souza, Guimarães, Otto R. Gottlieb, C. H. S. Andrade, Mauro Taveira Magalhães,

Traditional Chinese Medicine Analysis

Two new isoflavanones (1 and 13), along with 25 known compounds (2–12, 14–27), were isolated from the EtOAc-soluble fraction of the heartwood of Dalbergia odorifera by following their potential to inhibit the LPS-induced nitric oxide production in RAW 264.7 cells. The structures of the isolated compounds were established by spectroscopic data such as 1D, 2D NMR and MS spectrometry. Among the isolated compounds, (2S)-pinocembrin (26), showed the most potent inhibitory effect with IC50 value of 18.1 μM.