
The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator
2006; Bentham Science Publishers; Volume: 6; Issue: 5 Linguagem: Inglês
10.2174/138955706776876203
ISSN1875-5607
AutoresAna e Silva, Sérgio Veloso Brant Pinheiro, Regina Mara Silva Pereira, Ânderson Luiz-Ferreira, Robson A.S. Santos,
Tópico(s)Computational Drug Discovery Methods
ResumoIn this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2-Angiotensin-(1-7)-Mas axis.
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